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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
13.33
Human Site:
T702
Identified Species:
24.44
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
T702
T
S
E
E
M
Q
K
T
N
N
A
I
S
S
K
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
T702
T
S
E
E
M
Q
K
T
N
N
A
I
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
T702
I
S
E
E
M
Q
K
T
N
N
A
I
S
S
K
Dog
Lupus familis
XP_543184
1286
146207
A730
T
S
E
D
M
Q
K
A
N
S
A
I
S
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
S656
E
E
M
E
K
S
N
S
A
I
S
S
K
R
E
Rat
Rattus norvegicus
NP_001099552
648
74414
S131
I
L
H
R
D
I
K
S
Q
N
I
F
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
A347
Q
P
I
S
V
S
R
A
V
E
R
A
E
A
A
Chicken
Gallus gallus
XP_420401
1281
145243
P716
V
K
E
E
I
K
K
P
D
L
T
M
Q
N
K
Frog
Xenopus laevis
Q7ZZC8
944
104521
G427
T
V
C
I
T
D
E
G
Q
L
Y
S
F
G
S
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
Y180
E
L
C
E
G
K
P
Y
N
Q
K
S
D
I
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
K574
I
S
A
E
E
R
R
K
K
I
E
A
L
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
M89
G
Y
C
K
G
G
D
M
A
E
A
I
K
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
S341
I
R
A
E
I
D
A
S
L
R
R
E
W
E
V
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
93.3
80
N.A.
6.6
20
N.A.
0
26.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
26.6
33.3
N.A.
20
60
13.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
8
16
16
0
39
16
0
8
16
% A
% Cys:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
16
8
0
8
0
0
0
8
0
0
% D
% Glu:
16
8
39
62
8
0
8
0
0
16
8
8
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
8
0
0
0
16
8
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
31
0
8
8
16
8
0
0
0
16
8
39
0
8
0
% I
% Lys:
0
8
0
8
8
16
47
8
8
0
8
0
16
16
47
% K
% Leu:
0
16
0
0
0
0
0
0
8
16
0
0
16
0
0
% L
% Met:
0
0
8
0
31
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
39
31
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
31
0
0
16
8
0
0
8
0
0
% Q
% Arg:
0
8
0
8
0
8
16
0
0
8
16
0
0
8
0
% R
% Ser:
0
39
0
8
0
16
0
24
0
8
8
24
31
31
8
% S
% Thr:
31
0
0
0
8
0
0
24
0
0
8
0
0
8
8
% T
% Val:
8
8
0
0
8
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _